Surgical treatment of epilepsy induced by gray matter heterotopia

VernacularTitle:灰质异位所致癫痫的外科治疗
Author: Zhi-Gang LUO ¹ ; Yun-Lin TANG ; Lian-Yin ZHOU ; Hui ZHOU ; Yuan-Yuan BIAN ; Jian SHAN ; Yi-Sheng ZHANG
Author Information

1. 解放军第458医院
Keywords: Gray matter heterotopia; Epilepsy; Surgical procedures
From: Chinese Journal of Neuromedicine 2009;8(1):33-35
CountryChina
Language:Chinese
Abstract: Objective To explore the relationship between gray matter heterotopia and epilepsy and assess the therapeutic effect of surgical intervention. Methods Six cases of gray matter heterotopia-induced epilepsy treated in our department between May, 2004 and May, 2006 were analyzed retrospectively for the clinical characteristics, surgical approaches, and the outcomes in the 2- to 4-year-long follow-up. Results All the patients received surgical interventions through different approaches, including resection of the heterotopic gray matter plus bipolar coagulation of the cortexes in 4 cases, heterotopic gray matter resection with bipolar coagulation of the cortexes and temporal lobectomy in 1 case, and exclusive bipolar coagulation of the cortexes in 1 case. Five patients were free of seizure attach and 1 patient showed significantly reduced seizure attack after the operation. Conclusion Surgical intervention can be effective for treatment of intractable epilepsy induced by gray matter heterotopia.