Prevalence and Epidemiological Characteristics of Endoscopically Proven Reflux Esophagitis in Children in Korea.
10.5223/pghn.2017.20.3.160
- Author:
Aram YANG
1
;
Ben KANG
;
Jae Young CHOE
;
Hye Seung KIM
;
Kyunga KIM
;
Yon Ho CHOE
Author Information
1. Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. i101016@skku.edu
- Publication Type:Original Article
- Keywords:
Gastroesophageal reflux;
Prevalence;
Risk factors;
Endoscopy;
gastrointestinal;
Pediatrics
- MeSH:
Child*;
Endoscopy;
Endoscopy, Digestive System;
Esophagitis, Peptic*;
Gastroesophageal Reflux;
Humans;
Internship and Residency;
Korea*;
Logistic Models;
Multivariate Analysis;
Pediatrics;
Prevalence*;
Retrospective Studies;
Risk Factors
- From:Pediatric Gastroenterology, Hepatology & Nutrition
2017;20(3):160-166
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The prevalence of reflux esophagitis (RE) has increased recently in Korea. Little is known concerning the prevalence and characteristics of RE in pediatric patients. This study investigated the prevalence and influence of risk factors in endoscopically proven RE in Korea in pediatric patients over a period of 14 years. METHODS: A retrospective chart review of all patients between the ages of 1 month and 20 years who underwent esophagogastroduodenoscopy at Samsung Medical Center between 2001 and 2014 was carried out. Univariate and multivariate analyses were conducted to identify independent risk factors for RE. RESULTS: The prevalence rate of endoscopically proven RE in this study was 28.7% (978/3,413). The prevalence of RE increased from 11.8% from 2001 to 2007 to 37.7% from 2008 to 2014. Multivariate logistic regression analysis revealed that residency in the Greater Gangnam area (odds ratio [OR], 1.21; 95% confidence interval [CI], 1.02-1.44) and age (OR, 1.13; 95% CI, 1.11-1.15) were significant predictive factors for the presence of RE. CONCLUSION: The prevalence rate of endoscopically proven pediatric RE has increased over the past 14 years. Residency and older age are more important independent risk factors for pediatric RE in Korea.
