Clinical analysis of hypertrophic cranial pachymeulngitis
10.3760/cma.j.issn.1671-8925.2008.12.024
- VernacularTitle:肥厚性硬脑膜炎的临床分析
- Author:
Yan ZHANG
1
;
Ying-Ying SU
;
Fan-Heng HUANG
Author Information
1. 首都医科大学宣武医院
- Keywords:
Meningitis;
Magnetic resonance imaging;
Combined therapeutics
- From:
Chinese Journal of Neuromedicine
2008;7(12):1272-1275
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical characteristics of hypertrophic cranial pachymeningitis (HCP). Methods The clinical data of 10 HCP patients receiving comprehensive therapies in Xuanwu Hospital between 2004 and 2007 were retrospectively analyzed. Results All the 10 patients showed symptomatic improvements after the administration of effective treatment, including 8 with complete recovery, 1 with mild insufficiency in left eye abduction, and 1 with frequent mild headache after the treatments. During the follow-up for 6 months to two years, 2 patients experienced a single rclapsc and 1 had 3 relapses, who all responded favorably to therapy with corticosteroid hormones. Conclusion Early definite diagnosis of HCP can bc derived based on the clinical characteristics and results of laboratory examinations. Timely use of corticosteroid hormones and antibiotics can be essential to prevent the occurrence of irreversible nervous system impairment in these patients, and surgical removal of the lesions can be performed when necessary.