Clinical analysis of 57 cerebellar medulloblastoma cases
10.3760/cma.j.issn.1671-8925.2008.11.020
- VernacularTitle:57例髓母细胞瘤的临床回顾性分析
- Author:
Zhen-Hua YU
1
;
Chun-Long KE
;
Shun-Ye ZHU
;
Zhong-Qing RUAN
;
Zhi-Bo XIA
Author Information
1. 中山大学附属第一医院
- Keywords:
Medullublastoma;
Mierosurgery
- From:
Chinese Journal of Neuromedicine
2008;7(11):1163-1165
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical outcomes of patients undergoing microsurgery for cerebellar medulloblastoma. Methods This retrospective analysis of the clinical and follow-up data involves 57 patients who received microsurgery for pathologically confirmed cerebellar medulloblastorna, and the microsurgical techniques for medulloblastoma were discussed. Results Among the 57 patients, 42 had total tumor resection, 13 had subtotal and 2 had partial resection of the tumors. Patency of the midbrain aqueduct was achieved in all the cases after the surgery. Hydrocephalus was found in 43 patients before the operation and only in 16 patients after the operation. Tumor relapse occurred in 19 patients 2 years after the operation, including 8 with implantation metastasis compromising the central nervous system and 1 patient with frontal lobe metastasis who received reoperations. The earliest tumor relapse occurred 20 days after the surgery. The 2- and 5-year postoperative survival rates in these patients were 68.4% and 49.1%, respectively. Conclusion Good therapeutic effects can be achieved with total resection of the tumors and postoperative whole brain and spinal cord radiotherapy in patients with medulloblastomas.
