Change of blood rheology of acute cerebral infarction patients after using Cinepazide Maleate Injection

VernacularTitle:马来酸桂哌齐特注射液治疗急性脑梗死血液流变学变化及疗效观察
Author: Wen-Bo ZHANG ¹ ; Jia-Quan SHI
Author Information

1. 广东省梅州市人民医院
Keywords: Cerebral infarction; Blood rheology; Cinepazide Maleate Injection
From: Chinese Journal of Neuromedicine 2008;7(7):734-736
CountryChina
Language:Chinese
Abstract: Objective To study the effect of Cinepazide Maleate Injection on blood rheology of acute cerebral infarction patients. Methods 152 patients with cerebral infarction which attacked in 72 h after onset were separated into experimental group (n=88) and control group (n=64). 320 mg Cinepazide Maleate Injection was given to the experimental group and 20 mL Danshen Injection was given to control group, both by intravenous drip, once a day, for 14 d. The clinical efficacy and the changes of blood rheology were observed and compared in the 2 groups. Results The results of Chinese Stroke Scale (CSS) in the experimental group were significantly better than those in the control group (P<0.05), and the decrease in the parameters of blood rheology was much more obvious in the experimental group than in the control group (P<0.05) 2 weeks later. The excellent rate was 62.5% in the experimental group, which was higher than 35.9% in the control group significantly (P<0.05). Conclusion The Cinepazide Maleate Injection is effective in the treatment of acute cerebral infarction and can reduce the blood viscosity.