Relationship between intermediate hyperglycemia and acute cerebrovascular disease
10.3760/cma.j.issn.1671-8925.2008.07.023
- VernacularTitle:中间高血糖与急性脑血管病的关系
- Author:
Yan SHAO
1
;
Cheng-Guo ZHANG
;
Guang-Lun ZENG
;
Jian XIE
Author Information
1. 广东省佛山市第一人民医院
- Keywords:
Intermediate hyperglycemia;
Glucose tolerance;
Cerebrovascular disease;
Risk factor
- From:
Chinese Journal of Neuromedicine
2008;7(7):731-733
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between intermediate hyperglycemia and acutece rebrovascular disease. Methods 365 consecutive patients with acute cerebrovascular disease were enrolled. The fasting, non-fasting plasma glucose levels and lipid levels were measured. The non-diabetes patients undergone oral glucose tolerance test (OGTT) 1 week after the onset of the disease. All were classified as having normal glucose tolerance (NGT), intermediate hyperglycemia [IFG(impaired fasting glucose), IGT(impaired glucose tolerance), and co-existence of IFG and IGT] and diabetes mellitus (DM). The rates of the accepted risk factors for atherosclerosis (AS), the severity of the stroke and AS on B scan were compared among the groups. Results The rates of IFG, IGT, and co-existence of IFG and IGT were 1.37%, 24.66%, and 3.01%, respectively. The rate of hypertension was higher in DM subjects (P= 0.007) than in NGT subjects, while the rates in NGT subjects and in DM subjects compared with that in intermediate hyperglycemia subjects were not of statistical significance (P>0.05). And there were no statistical significances in the rates of smoking, drinking and dyslipidemia. Meanwhile no statistical significances were found in the severity of the stroke and the signs of AS detected by duplex scanning (P>0.05). Conclusion Intermediate hyperglycemia is common in the patients with acute cerebrovascular disease. R is important in the pathogenesis of cerebrovascular disease when combined with the other risk factors for AS.
