Report of 51 cases with giant pituitary adenoma

VernacularTitle:巨大型垂体腺瘤51例报告
Author: Pei WANG ¹ ; Yu-Yu WANG ; Guang-Yang REN ; Chun-Yue YOU ; Zong-Fen CHEN ; Shun-Wu XIAO ; Xue-Jun ZHANG ; Yin DAI
Author Information

1. 遵义医学院附属医院
Keywords: Pituitary adenoma; Microsurgery; Bromocriptine; T-knife
From: Chinese Journal of Neuromedicine 2008;7(6):621-623
CountryChina
Language:Chinese
Abstract: Objective To summarize the experience of microsurgical operation via single nostril-sphenoid sinus approach or via subfrontal approach on giant pituitary adenoma. Methods Microsurgical operations were performed on 51 cases of giant pituitary adenoma via single nostril-sphenoid sinus approach (n=13) or via subfrontal approach (n=38). Results Total resection was achieved in 18 cases by the operation via subfrontal approach, most resection in 13 cases, partial resection in 4 cases, postoperative death in 3 cases. Another a few patients were operated via single nostril-sphenoid sinus approach, in which total resection was executed in 7 cases, most resection in 4cases, partial resection in 2 cases. The statistical differences in the total removal rate and curative effect were meaningless between the two groups. Conclusion The giant pituitary adenoma can be treated by microsurgical operation via single nostril-sphenoid sinus approach or via subfrontal approach. The cure rate of giant pituitary adenoma can be increased by postoperative treatments with bromocriptine and γ-knife.