Effects of astragalus membranaceus parenteral solution on nerve function and hemorheology of gerontal cerebral infarction patients
10.3760/cma.j.issn.1671-8925.2008.04.020
- VernacularTitle:黄芪注射液对老年脑梗死患者神经功能和血液流变学的影响
- Author:
Jing-Ya JIAO
1
;
Jun-Zhi LI
Author Information
1. 河北省安国市医院
- Keywords:
Cerebral infarction;
Aged;
Astragalus membranaceus;
Neurologic impairment;
Ability of activities of daily living;
Hemorheology
- From:
Chinese Journal of Neuromedicine
2008;7(4):399-401,405
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the therapeutic effects of astragalus membranaceus parenteral solution on the elders with cerebral infarction and its influences on patients' nerve function,activities of daily living and hemorheology. Methods Ninety-two patients diagnosed with cerebral infarction who were older than 60 years were randomly divided into astragalus membranaceus group(n=50) and control group (n=42). The two groups were treated with conventional therapy. But based on conventional therapy, astragalus membranaceus parenteral solution (30 mL, 2 g/mL) added into 5%glucose saline was used in the astragalus membranaceus group once daily for 4 weeks. The clinical therapeutic effects, nerve function, ability of activities of daily living and hemorheology were compared between the 2 groups. Results The total effective rate of the astragalus membranaceus group was not significantly different from that of the control group (P>0.05), while the excellent rate and therapeutic effects of the astragalus membranaceus group was significantly higher than that of the control group (P<0.05). Compared with control group, the scores of the neurologic impairment were decreased significantly(P<0.05), Barthel index was increased significantly (P<0.05), whole blood viscosity, hematocrit and fibrinogen were decreased significantly (P<0.05) in the astragalus membranaceus group. Conclusions Astragalus membranaceus parenteral solution can improve nerve function and the ability of activities of daily living of the gerontal cerebral infarction patients.