Curative effect of EEG localization and microsurgery for intractable epilepsy
10.3760/cma.j.issn.1671-8925.2008.03.004
- VernacularTitle:脑电定位与手术治疗难治性癫痫疗效观察
- Author:
Shi-Bin YAO
1
;
An-Min LI
;
Shu-Li LIANG
;
Hong-Da ZHANG
Author Information
1. 解放军总医院附属第一医院
- Keywords:
Intractable epilepsy;
Electroencephalography;
Ambulatory EEG monitoring Electroconicogram monitoring
- From:
Chinese Journal of Neuromedicine
2008;7(3):226-228
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the epileptogenic focus locating methods before and during operation and the curative effect of surgical treatment on the basis of localization. Methods Epileptogenic foci in 621 cases of intractable epilepsy were localized according to clinical manifestations and imaging findings by routine EEG (REEG), ambulatory EEG (AEEG) or video-EEG (VEEG).Different types of operations were performed based on the categories of epilepsy, the preoperatively localized foci and electrocorticogram (ECoG) monitoring results during operations. Results The follow-up ranging 0.5-4 years revealed, according to the criteria of International Antiepileptic Association,that 340 cases(54%)were completely recovered(no postoperative seizure),223 cases(36%)were improved obviously (seizure frequency was decreased by more than 75%), 37 cases (6%) were improved a little(seizure frequency was decreased by 50%-75%)and 21(3%)were not improved(seizure frequency was decreased by less than 50%): the effective rdte was 97%.No case worsened.Conclusions Preoperative integrated localization by EEG principally and intraoperative ECoG monitoring can effectively confirm the site and size of epileptogenic foci to instruct the operation and prevent complications so that the satisfactory treatment efficacy can be achieved.
