Distribution characteristics and drug resistance rate of pathogenic bacteria in patients with pulmonary tuberculosis combined with Candida infection on the Tibetan plateau
10.12206/j.issn.2097-2024.202304014
- VernacularTitle:青藏高原肺结核合并念珠菌感染患者的病原菌分布特点及耐药率分析
- Author:
Shenghui SHI
1
;
Fei SHI
1
;
Qiong LEI
2
;
Yafeng WANG
1
;
Xuehua WU
1
Author Information
1. Department of Pharmacy, Qinghai Provincial People’s Hospital, Xining 810007, China.
2. Department of Pharmacy, Qinghai Fourth People's Hospital, Xining 810007, China.
- Keywords:
pulmonary tuberculosis;
Candida;
etiology;
drug resistance
- From:
Journal of Pharmaceutical Practice and Service
2024;42(6):260-262
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pathogenic distribution characteristics and drug resistance of opportunistic Candida in patients with pulmonary tuberculosis on the Qinghai-Tibet Plateau. Methods 3 012 hospitalized cases of pulmonary tuberculosis at Qinghai Province Fourth People’s Hospital from March 1, 2020 to December 31, 2020 were analyzed, sputum samples were collected, Candida identification was carried by VITEK-32-YBC automatic bacterial analysis system, and the detected Candida was tested for drug sensitivity. Results Among the 3 012 cases of pulmonary tuberculosis in this investigation, 283 cases of pulmonary tuberculosis patients with Candida infection, accounting for 9.40%. Among them, Candida albicans was the main type of Candida, accounting for 79.86% of the total. Conclusion The prevalence rate of pulmonary tuberculosis complicated with Candida infection was high in Qinghai-Tibet Plateau. Therefore, the selection of antimicrobial drugs should be based on a comprehensive analysis of the patient's condition, in order to select the best and most effective drugs for treatment.
