Advances in the multi-omics research on nonalcoholic fatty liver disease

VernacularTitle:非酒精性脂肪性肝病多组学研究现状
Author: Mingxiu DUAN ¹ ; Xinli CHEN ¹ ; Weiyu CHANG ¹ ; Yuan YANG ¹ ; Shiqi YANG ¹ ; Hui WU ¹
Author Information

1. Centre for Clinical Pharmacy， The First Affiliated Hospital of Kunming Medical University， Kunming 650000， China
Publication Type:Review
Keywords: Non-alcoholic Fatty Liver Disease; Genomics; Proteomics; Metabolomics; Gastrointestinal Microbiome
From: Journal of Clinical Hepatology 2024;40(6):1240-1247
CountryChina
Language:Chinese
Abstract: The prevalence rate of nonalcoholic fatty liver disease （NAFLD） reaches up to 30% around the world， and the disease has a serious impact on human health and constitutes a public health burden. Due to difficulties in the diagnosis and monitoring of NAFLD， it is important to identify potential drug targets and biomarkers， and multi-omics techniques hold great promise in the search for early diagnostic markers， therapeutic targets， and outcome and prognostic assessment of NAFLD. This article reviews the research advances in multi-omics techniques in the field of NAFLD in recent years， in order to provide a richer theoretical basis and new strategies for the prevention and treatment of NAFLD.