Factors affecting health-related quality of life in patients with Parkinson's disease
10.19845/j.cnki.zfysjjbzz.2023.0064
- VernacularTitle:帕金森病患者健康相关生活质量影响因素分析
- Author:
Detao MENG
1
;
Boyan FANG
1
Author Information
1. Parkinson Medical Center,Beijing Rehabilitation Hospital,Capital Medical University,Beijing 100144,China
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
Motor symptoms;
Non-motor symptoms;
Health-related quality of life
- From:
Journal of Apoplexy and Nervous Diseases
2023;40(3):253-256
- CountryChina
- Language:Chinese
-
Abstract:
Objective Our objective was to identify factors predicting health-related quality of life (HRQoL) in patients with Parkinson's disease (PD) Methods A cross-sectional study was carried out in 161 PD patients. QoL was assessed with the PDQ-39.Motor symptoms and non-motor symptoms were evaluated by a list of assessment tools including the Hoehn and Yahr scale,The Movement Disorder Society Unified Parkinson Disease Rating Scale et al. The Spearman correlation coefficient r was used to evaluate the correlation between PDQ-39 and motor and non-motor factors. Multiple linear regression models were used to demonstrate whether the factors investigated contribute significantly to QoL. Results PDQ-39 Summary Index was highly correlated with Voice handicap index(r=0.616) and correlated at a moderate level (r=0.30-0.50) with UPDRS-I,UPDRS-II,Parkinson Fatigue Scale,Modified Apathy Evaluation Scale,Geriatric Depression Scale,Gait and Falls Questionnaire,Eating Assessment Tool Scale. Depression,gait,swallowing,voice handicap and gender were independent predictors of HRQoL in the multivariate analysis model. Depression showed to be the most consistent determinant of HRQoL,followed by gait problems,swallowing,voice handicap and gender. Conclusion Depression,gait problems,swallowing,voice handicap and gender are significant factors contributing to a poor quality of life in Parkinson's disease patients. Swallowing and voice handicap,as well as depression,gait problems that are widely recognized,are also factors that cannot be ignored.
- Full text:2024061722210268180Factors affecting health-related quality of life in patients with Parkinson's disease.pdf
