Progress in the Diagnosis and Treatment of Infantile Epileptic Spasm Syndrome

VernacularTitle:婴儿癫痫性痉挛综合征诊治进展
Author: Lu ZHENG ^{1
,

2} ; Ting YANG ; Chaoyang CHEN ; Ran WEI ; Xuanling ZHANG ; Yijie MA ; Ying ZHOU
Author Information

1. 北京大学第一医院药剂科,北京 100034
2. 北京大学第一医院太原医院药剂科,太原 030000
Keywords: rare dieases; infantile epileptic spasm syndrome; antiepileptic
From: JOURNAL OF RARE DISEASES 2024;3(2):260-268
CountryChina
Language:Chinese
Abstract: Infantile epileptic spasm syndrome(IESS)is a new concept proposed recently.IESS is a unique and age-specific refractory epilepsy syndrome.The recent advances in molecular biology,neuroimmunol-ogy and the in-depth study of anti-epileptic mechanism in antiepileptic drugs have led to the achievements in the definition and treatment of infantile epileptic spasm.At present,the use of traditional antiepileptic drugs is de-creasing,while the use of new antiepileptic drugs is increasing.In this paper,based on the relevant literature in recent years,the authors discuss the pathogenesis,epidemiology,etiology,diagnosis,treatment,therapeutic drugs,clinical progress,efficacy,and safety of infantile epileptic spasm,hoping to introduce the latest status in research and achievements of IESS.