- VernacularTitle:视神经脊髓炎谱系疾病的疾病修饰治疗进展
- Author:
Xuanling ZHANG
1
;
Chaoyang CHEN
1
;
Ran WEI
1
;
Ying ZHOU
2
Author Information
- Publication Type:Review
- Keywords: neuromyelitis optic spectrum disorders; disease-modifying therapy; medication
- From: JOURNAL OF RARE DISEASES 2024;3(2):246-251
- CountryChina
- Language:Chinese
-
Abstract:
Neuromyelitis optic spectrum disorders (NMOSD) is a serious inflammatory demyelinating disease. Clinical treatment of NMOSD mainly involves acute phase treatment and remission phase prevention treatment. Disease-modifying therapy (DMT) in remission phase of NMOSD can effectively reduce disease recurrence and delay disability progression. At present, the drugs commonly used for DMT at home and abroad include classical immunosuppression, B-cell surface antigen monoclonal antibody, complement targeting monoclonal antibody, IL-6 receptor-targeting monoclonal antibody, etc. This paper mainly reviews the DMT drugs efficacy, safety, as well as the marketing status of NMOSD.