Mechanism of cuproptosis in Wilson's disease based on the importance of copper homeostasis
- VernacularTitle:基于铜稳态重要性探讨铜死亡在肝豆状核变性中的发生机制
- Author:
Shupei JIA
1
;
Wenming YANG
1
;
Guran YU
1
Author Information
- Publication Type:Journal Article
- Keywords: Cuproptosis; Copper metabolism disorder
- From: Journal of Apoplexy and Nervous Diseases 2023;40(7):663-666
- CountryChina
- Language:Chinese
- Abstract: Copper plays a very important role in the physiological activities of the body. Copper metabolism disorders due to various reasons can disrupt the copper homeostasis of the body to cause a deficiency or excess of copper,resulting in a series of pathological processes that eventually lead to cell death and organ dysfunction. Cuproptosis,a newly discovered cell death mechanism,is related to copper overload. Cuproptosis has been confirmed in Wilson's disease,which is of great significance for future research on the mechanism and treatment of copper metabolism disorders.
- Full text:2024061614303583761基于铜稳态重要性探讨铜死亡在肝豆状核变性中的发生机制.pdf
