Clinical observation of antibacterial photodynamic therapy assisted subgingival curettage for the treatment of chronic periodontitis
10.12016/j.issn.2096-1456.2024.06.007
- VernacularTitle:抗菌光动力疗法辅助龈下刮治治疗慢性牙周炎临床效果观察
- Author:
Xinlin WANG
1
;
Wenjun TANG
;
Yiyang JIANG
;
Yan SHI
;
Ziqi YAN
;
Dongqing WANG
Author Information
1. 首都医科大学附属北京口腔医院牙周科,北京(100050)
- Keywords:
chronic periodontitis;
antibacterial photodynamic therapy;
periodontal initial therapy;
scaling and root planing;
probing depth;
plaque index;
bleeding index;
bleeding on probing
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2024;32(6):451-456
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of antibacterial photodynamic therapy(aPDT)as an adjunct to subgingival scaling and root planning in the treatment of chronic periodontitis.Methods This study followed medical ethics guidelines,and informed consent was obtained from all patients.Sixteen patients were recruited for this random-ized split-mouth controlled trial.The control group underwent subgingival scaling and root planning(SRP),while the ex-perimental group received subgingival scaling and root planing plus aPDT treatment using Perowave? with a toluidine blue O solution photosensitizer.The probing pocket depth(PD),recession,plaque index(PLI),bleeding index(BI)and proportion of positive sites of bleeding on probing(BOP)(BOP%)at all sites were examined at baseline(before treat-ment)and at 1,3 and 6 months after treatment.Results Follow-up was completed for 13 patients.On the control side,356 teeth were tested at 2 136 sites.A total of 360 teeth on the test side and 2 160 sites were included in the study.Before treatment,there was no significant difference in the baseline indicators between the two groups.After treatment,both groups showed significant improvement in clinical parameters,including PD,PLI,BI,and BOP%,compared with baseline.At 3 months,the BOP%and PLI in the experimental group were significantly lower than those in the control group(P＜0.05).The improvement in BOP%and PLI in the experimental group was significantly greater than that in the control group 3 months after treatment(P＜0.05).Conclusion aPDT,as an adjuvant treatment to SRP for chronic periodontitis,can improve gingival bleeding and control periodontal inflammation in the early stage.
