Superficial siderosis of the central nervous system：A literature analysis and case report
- VernacularTitle:中枢神经系统表面铁沉积症的临床分析
- Author:
Ruolin ZHOU
1
;
Haining ZHANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Central nervous system; Hemosiderin deposition; Ataxia
- From: Journal of Apoplexy and Nervous Diseases 2023;40(12):1089-1095
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the etiology，clinical manifestations，imaging features，and treatment of superficial siderosis of the central nervous system （SSCNS）. Methods A patient confirmed with SSCNS was reported.Sixty-one patients confirmed with SSCNS were found through a search of China National Knowledge Infrastructure and Wanfang Data and were analyzed in categories for the epidemiology， etiology， clinical manifestations， and laboratory test results. Results Among the 61 patients with SSCNS reported in the literature， ataxia was the most common clinical symptom （49 cases， 80%）， followed by hearing loss （43 cases，70%） and pyramidal signs（30 cases， 49%）.A probable cause was found in 25 （39%） of these cases. Conclusion SSCNS can last for several years or even decades， with hearing loss， ataxia， and pyramidal signs as its main clinical symptoms.Magnetic resonance imaging is the most valuable basis for diagnosis， and susceptibility-weighted imaging is more sensitive in the diagnosis of microhemorrhage.
- Full text:2024061221402450894中枢神经系统表面铁沉积症的临床分析.pdf
