Mechanism of exosome in the pathogenesis of prostate cancer and its potential diagnostic application
10.3969/j.issn.1009-8291.2024.02.018
- VernacularTitle:外泌体在前列腺癌发生发展中的作用及在诊断方面的应用前景
- Author:
Jingdong XUE
1
;
Denglong WU
1
Author Information
1. Department of Urology, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, China
- Publication Type:Journal Article
- Keywords:
exosome;
prostate cancer;
tumor markers;
tumor drug resistance;
tumor microenvironment;
cell to cell commu-nication;
epithelial mesenchymal transformation
- From:
Journal of Modern Urology
2024;29(2):187-191
- CountryChina
- Language:Chinese
-
Abstract:
Prostate cancer (PCa) is one of the most common tumors in men.In recent years, various researches on this disease and clinical applications have benefited patients.Exosome is a subclass of extracellular vesicles (EVs).Many studies have explored the mechanisms of exosome in mediating epithelial mesenchymal transformation, angiogenesis, tumor microenvironment establishment, immune escape and drug resistance acquisition in PCa, which provides a new perspective for finding new diagnostic markers.This article reviews the role of exosome in the pathogenesis of PCa and its diagnostic application.
