Liquid biopsy using urinary cell-free DNA is significant in the detection and treatment of urologic diseases
10.3969/j.issn.1009-8291.2024.04.018
- VernacularTitle:尿游离DNA的液体活检有望成为泌尿系疾病诊治的重要方向
- Author:
Yuting LIU
1
;
Weixia LI
2
;
Mengchen XIE
1
;
Yangyang GUO
1
;
Xin WANG
1
Author Information
1. Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029
2. The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210029, China
- Publication Type:Journal Article
- Keywords:
urine;
cell-free DNA;
urologic diseases;
biomarkers;
liquid biopsy
- From:
Journal of Modern Urology
2024;29(4):379-382
- CountryChina
- Language:Chinese
-
Abstract:
Urine is produced from the urinary system, and urinary cell-free DNA (cfDNA) carries genomic DNA directly secreted from urinary system.Urine samples are non-invasive, unlimited in quantity and easy to obtain, making urinary cfDNA a promising biomarker for urologic diseases.This article reviews the progress of clinical application of urinary cfDNA in urologic diseases.