Sacral neuromodulation effective for neurogenic bladder: a Meta-analysis
10.3969/j.issn.1009-8291.2024.04.013
- VernacularTitle:骶神经调控术对神经源性膀胱疗效的Meta分析
- Author:
Yuhang SU
1
;
Wenqiang QI
1
;
Benkang SHI
1
Author Information
1. Department of Urology, Qilu Hospital of Shandong University, Ji’nan 250012, China
- Publication Type:Journal Article
- Keywords:
sacral neuromodulation;
neurogenic bladder;
lower urinarytract dysfunction;
lower urinary tract symptoms;
urinary frequency;
daily episodes of urinary incontinence;
single void volume;
maximum flow rate;
residual urine;
maximum bladder capacity;
bladder compliance
- From:
Journal of Modern Urology
2024;29(4):353-358
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To evaluate the efficacy of sacral neuromodulation (SNM) in the treatment of neurogenic bladder (NB) with Meta-analysis, so as to provide reference for clinical treatment options for NB. 【Methods】 Relevant literatures regarding the efficacy of SNM in treating NB during Jan.2010 and Dec.2022 were collected from the PubMed and CNKI databases, and screened with inclusion and exclusion criteria.After the quality of literatures was assessed, data were extracted and then analyzed using Review Manager 5.3. 【Results】 The research included 14 studies involving 601 patients.Meta-analysis showed that SNM significantly improved urinary frequency (WMD=4.30, 95%CI: 2.84-5.77, P<0.01), daily episodes of urinary incontinence (WMD=2.92, 95%CI: 2.76-3.07, P<0.01), single void volume (WMD=-113.93, 95%CI: -159.91- -67.98, P<0.01), maximum flow rate (WMD=-3.23, 95%CI: -4.04- -2.42, P<0.01), residual urine (WMD=111.79, 95%CI: 79.93-143.64, P<0.01), maximum bladder capacity (WMD=-65.63, 95%CI: -84.38- -46.88, P<0.01), and bladder compliance (WMD=-4.65, 95%CI: -8.75- -0.55, P=0.03). 【Conclusion】 SNM is effective in the treatment of NB, but more randomized controlled trials are needed to verify the efficacy.