Changes and influencing factors of pulse wave transit time in hypertensive patients after administration of nifedipine controlled-release tablets
- VernacularTitle:高血压患者服用硝苯地平控释片后脉搏波传导时间的变化及影响因素
- Author:
Li WANG
1
;
Chen SHAN
2
;
Kechun LIU
3
Author Information
- Publication Type:Journal Article
- Keywords: nifedipine; hypertension; pulse wave transit time (PWTT)
- From: Journal of Xi'an Jiaotong University(Medical Sciences) 2024;45(2):258-261
- CountryChina
- Language:Chinese
- Abstract: 【Objective】 To explore the effect of nifedipine controlled-release tablets on left wrist pulse wave transit time (PWTT) in hypertensive patients. 【Methods】 We selected 262 essential hypertensive patients hospitalized at Chinese PLA General Hospital Hainan Branch from August 2021 to December 2022. The patients were divided into observation group (n=140) and control group (n=122) according to whether or not taking nifedipine controlled release tables. The left wrist PWTT at 0.5 h, 2.5 h, 4.5 h, 6.5 h and 8.5 h after administration of the medicine was collected with a smart watch for statistical analysis. 【Results】 ①The PWTT in the observation group (93±15, 93±13, 87±15, 85±15, 84±10) and the control group (98±18, 92±16, 90±10, 89±8, 89±9) decreased gradually with the extension of time (F=11.448, P<0.001). ②The PWTT decreased by the same amplitude (F=2.206, P>0.05). ③There was no significant difference in PWTT between the observation group and the control group at five time points (F=1.164, P>0.05). 【Conclusion】 Administration of nifedipine controlled-release tablets does not affect PWTT of primary hypertensive patients’ left wrist.
