Discussion on Disease Mechanism of Autism Spectrum Disorders from the Concepts of “Vital Activity” and “Qi Configuration”
10.13288/j.11-2166/r.2024.03.006
- VernacularTitle:从“神机”与“气立”探讨孤独症谱系障碍的发病机制
- Author:
Lyuyuan LIANG
1
;
Weili DANG
2
;
Jiexin SU
1
;
Lingjia REN
1
;
Jialei CAO
1
;
Bingqi WEI
1
;
Bingxiang MA
2
;
Yamin KONG
2
Author Information
1. School of Pediatrics， Henan University of Chinese Medicine， Zhengzhou， 450046
2. First Affiliated Hospital of Henan University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
autism spectrum disorders;
vital activity;
qi configuration;
children
- From:Journal of Traditional Chinese Medicine
2024;65(3):256-260
- CountryChina
- Language:Chinese
-
Abstract:
This paper explored the disease mechanism of autism spectrum disorders （ASD） from the perspectives of “vital activity” and “qi configuration”， and it is believed that “vital activity” represents the internal regulatory mechanisms of the human body， while “qi configuration” represents the ability of the body to communicate and adapt to the external environment. Abnormal genetic factors lead to the extinction of vital activity in children with ASD， resulting in increased susceptibility to ASD. Environmental instability leads to the solitary qi configuration in ASD， triggering and exacerbating the manifestations of ASD on the basis of genetic susceptibility. In addition， epigenetic mechanisms also play an important role in the pathogenesis of ASD. Imbalances in vital activity and disruptions in qi configuration result in failure in qi transformation of zang-fu organs， with abnormal symptoms manifested through the five orifices. It is proposed that the treatment of ASD should aim to achieve a harmonious interaction between “vital activity” and “qi configuration” to accelerate the recovery of affected children.
