Interrelationship of Sarcopenia and Cardiovascular Diseases: A review of potential mechanisms and management
https://doi.org/10.15605/jafes.039.01.03
- Author:
Frederick Berro Rivera
1
;
Bettina Therese Escolano
2
;
Frances Micole Nifas
2
;
Sarang Choi
2
;
Genquen Philip Carado
3
;
Edgar Lerma
4
;
Krishnaswami Vijayaraghavan
5
;
Marc Gregory Yu
6
Author Information
1. Lincoln Medical Center, New York (NY), USA
2. Ateneo de Manila School of Medicine and Public Health, Pasig City, Philippines
3. College of Medicine, University of the East Ramon Magsaysay Memorial Medical Center, Philippines
4. Section of Nephrology, University of Illinois at Chicago College of Medicine, Chicago, Illinois, USA
5. University of Arizona, Phoenix, Arizona, USA
6. Section of Vascular Cell Biology, Joslin Diabetes Center and Harvard Medical School, Boston, USA
- Publication Type:Review
- MeSH:
Sarcopenia;
Cardiovascular Diseases
- From:
Journal of the ASEAN Federation of Endocrine Societies
2024;39(1):69-78
- CountryPhilippines
- Language:English
-
Abstract:
Sarcopenia refers to an age-related reduction of lean body mass. It showed a reciprocal relationship with cardiovascular diseases. Thus, it is imperative to explore pathophysiological mechanisms explaining the relationship between sarcopenia and cardiovascular diseases, along with the clinical assessment, and associated management. In this review, we discuss how processes such as inflammation, oxidative stress, endothelial dysfunction, neural and hormonal modifications, as well as other metabolic disturbances influence sarcopenia as well as its association with cardiovascular diseases. Moreover, this review provides an overview of both non-pharmacological and pharmacological management for patients with sarcopenia and cardiovascular diseases, with a focus on the potential role of cardiovascular drugs to mitigate sarcopenia.
- Full text:2024060316412422365jafes 11.pdf
