Characteristics and prevalence of Metabolic Syndrome among adult Filipinos with hypothyroidism: A cross-sectional study
https://doi.org/10.15605/jafes.039.01.13
- Author:
Harold Henrison Chiu
1
,
2
,
3
;
Emilio Villanueva III
4
;
Ramon Larrazabal Jr.
5
;
Anna Elvira Arcellana
1
;
Cecilia Jimeno
1
Author Information
1. Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Philippine General Hospital, University of the Philippines Manila
2. Department of Biochemistry and Molecular Biology, UP College of Medicine, University of the Philippines Manila
3. Section of Endocrinology, Department of Internal Medicine, Cardinal Santos Medical Center
4. Department of Pathology, College of Medicine, University of the Philippines Manila
5. Department of Medicine, Philippine General Hospital, University of the Philippines Manila
- Publication Type:Journal Article
- MeSH:
Dyslipidemias;
Hypothyroidism;
Metabolic Syndrome;
Prevalence
- From:
Journal of the ASEAN Federation of Endocrine Societies
2024;39(1):53-60
- CountryPhilippines
- Language:English
-
Abstract:
Objectives:We determined the clinical characteristics and prevalence of metabolic syndrome among adult Filipinos with overt hypothyroidism.
Methodology:This is a cross-sectional study of 151 adults. Patients were recruited by sequential enrollment. Anthropometric and blood pressure measurements were performed followed by blood extraction for metabolic parameters and thyroid function tests. Clinical and laboratory characteristics were compared between patients with and without metabolic syndrome.
Results:The prevalence of metabolic syndrome is 40.4% (95%CI: 32.5%, 48.7%). Patients with metabolic syndrome have a waist circumference of 88.4 ± 7.7 cm in females and 93.3 ± 9.0 cm in males. The median fasting blood glucose was 111.4 (52.2) mg/dL, median systolic blood pressure of 120 (30) mm Hg and diastolic blood pressure of 80 (20) mmHg, median serum triglycerides of 174.3 (114.2) mg/dL, median HDL-C of 42.3 (19.2) mg/dL and a proportion of patients with diabetes (23.0%) and hypertension (44.3%), respectively. The presence of increased waist circumference is the most prevalent component seen among hypothyroid patients. There were no differences in terms of age, sex, etiology of hypothyroidism and anti-TPO levels in those with and without metabolic syndrome.
Conclusion:The prevalence of metabolic syndrome in adult Filipinos with hypothyroidism is high. Emphasis must be placed on early screening using waist circumference and metabolic parameters among hypothyroid patients who are at high risk of developing metabolic syndrome.
- Full text:2024060316342023947jafes 9.pdf
