Genetic factors, risk factors and pathogenesis of cerebral palsy comorbid epilepsy

VernacularTitle:脑性瘫痪共病癫痫的遗传因素、危险因素及发病机制
Author: Chao GONG ¹ ; Beibei LIAN ¹ ; Xuemei LI ^{1
,

2} ; Peng ZHANG ^{1
,

3} ; Fanxu SONG ^{1
,

2} ; Jin GUO ^{1
,

3}
Author Information

1. Rehabilitation Medical College of Jiamusi University, Jiamusi, Heilongjiang 154007, China
2. Department of Pediatric Cerebral Palsy, The Third Affiliated Hospital of Jiamusi University
3. Department of Pediatric Neurology, The Third Affiliated Hospital of Jiamusi University
Publication Type:Journal Article
Keywords: cerebral palsy; epilepsy; genetic factors; pathogenesis
From: Chinese Journal of Child Health Care 2024;32(2):174-180
CountryChina
Language:Chinese
Abstract: Compared to the general population, there is a higher prevalence of epilepsy in individuals with cerebral palsy (CP). Epilepsy serves as an indicator of CP severity and has a significant impact on the early survival and future quality of life of children with CP. Therefore, it is crucial to investigate the shared mechanisms underlying CP and epilepsy. This study aims to summarize the comorbidity of CP and epilepsy from genetic factors, risk factors, and pathophysiological mechanisms, in order to provide a reference for further research.