Risk factors of non-alcoholic fatty liver disease in children
10.11852/zgetbjzz2023-0676
- VernacularTitle:儿童非酒精性脂肪性肝病危险因素的研究进展
- Author:
Zuotao GENG
1
;
Dan ZHANG
2
;
Xiaotong ZHU
2
;
Lanyi LI
2
;
Xuehai LI
1
;
Yongli YANG
1
Author Information
1. Department of Pediatrics, Women and Children′s Hospital of Lijiang, Lijiang, Yunan 674100, China
2. Department of Gastroenterology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunan 650032, China
- Publication Type:Journal Article
- Keywords:
non-alcoholic fatty liver disease;
chronic liver disease;
children
- From:
Chinese Journal of Child Health Care
2024;32(4):412-418
- CountryChina
- Language:Chinese
-
Abstract:
Non-alcoholic fatty liver disease(NAFLD) has become the main cause of chronic liver disease in children worldwide, and the incidence of NAFLD shows an increasing trend year by year. The risk factors leading to the onset of NAFLD in children are diversified and different from those in adults. At present, most medical institutions still pay little attention to NAFLD in children. This paper summarizes the risk factors and mechanisms for NAFLD in children, including gene polymorphism, maternal and fetal conditions, diet and living habits, environmental exposure, metabolic syndrome, endocrine-related mechanisms and intestinal microecology, in order to provide reference for the prevention and management of childhood NAFLD.