Epidemiologic study of Kawasaki disease in 6 months old and younger infants.
10.3345/kjp.2008.51.12.1320
- Author:
Yong Won PARK
1
;
Ji Whan HAN
;
In Sook PARK
;
Chang Hwi KIM
;
Sung Ho CHA
;
Jae Sook MA
;
Joon Sung LEE
;
Tae Chan KWON
;
Sang Bum LEE
;
Chul Ho KIM
;
Heung Jae LEE
;
Yong Soo YUN
Author Information
1. Department of Pediatrics, College of Medicine, Inje University, Seoul, Korea. yongpw@hanmail.net
- Publication Type:Original Article
- Keywords:
Mucocutaneous lymph node syndrome;
Coronary aneurysm;
Epidemiology;
Infant
- MeSH:
Age of Onset;
Aged;
Aneurysm;
Coronary Aneurysm;
Echocardiography;
Epidemiologic Studies;
Female;
Humans;
Incidence;
Infant;
Korea;
Male;
Mucocutaneous Lymph Node Syndrome;
Retrospective Studies
- From:Korean Journal of Pediatrics
2008;51(12):1320-1323
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The aim of this study was to investigate the epidemiologic status of Kawasaki disease (KD) in infants < or =6 months of age. METHODS: For the epidemiologic study of KD in Korea, data from 22,674 KD patients were collected from 1997 to 2005 on a 3 -year basis by a retrospective survey. From this survey, data of 1,739 KD patients < or =6 months of age were analyzed and compared with those of KD patients >6 months of age. RESULTS: A total of 1,739 patients < or =6 months of age, including 1,088 males and 651 females, represented 7.7% of total KD patients. These subjects included 22 patients aged <1 month, 171 patients aged 1-2 months, 304 patients aged 2-3 months, 407 patients aged 3-4 months, 372 patients aged 4-5 months, and 463 patients aged 5-6 months. Their mean age of onset was 4.3 months, and the male-to-female ratio was 1.67 :1 . Incidences of coronary arterial (CA) abnormalities (21.0% versus 18.7%) and CA aneurysms (4.7% versus 3.1%) detected by echocardiography showed differences between patients with KD younger and older than 6 months, respectively. CONCLUSION: Comparison of data from KD patients >6 months old with data from 1,739 KD patients < or =6 months old showed significantly higher incidences of CA abnormalities and CA aneurysms in the younger patients.
