Potential role of cerebellin family in Zika virus biosecurity events
10.13200/j.cnki.cjb.004229
- VernacularTitle:小脑蛋白家族在寨卡病毒生物安全事件中的潜在作用
- Author:
DU Jinfeng
- Publication Type:Journal Article
- Keywords:
Biosecurity;
Cerebellin(Cbln)family;
Zika virus;
Nervous system development;
Pathogenesis
- From:
Chinese Journal of Biologicals
2024;37(5):621-626
- CountryChina
- Language:Chinese
-
Abstract:
Zika virus can cross biological barriers to infect the nervous system,causing serious public health issues. As a key regulator of nervous system development,cerebellin(Cbln)family may have an interrelationship of interference and regulation with Zika virus. Due to the pathogenic characteristics of Zika virus,the functional characteristics of Cbln family and its effect in the nervous system,Cbln family is expected to become an important molecular marker and therapeutic target after Zika virus infection. This paper reviews the potential pathogenic and immunological relationships between Zika virus and Cbln family,and explores the important role of Cbln in maintaining nervous system function and ensuring biosecurity
