Hepatitis B vaccine： From prevention to treatment
- VernacularTitle:乙型肝炎疫苗——从预防到治疗
- Author:
Yisi LIU
1
;
Shan REN
1
;
Sujun ZHENG
1
;
Xinyue CHEN
1
Author Information
- Publication Type:Review
- Keywords: Hepatitis B， Chronic; Hepatitis B Vaccines; Clinical Trial
- From: Journal of Clinical Hepatology 2024;40(5):1021-1025
- CountryChina
- Language:Chinese
- Abstract: Hepatitis B vaccination is the most economical and effective way to prevent HBV infection. The advances in molecular biology and genetic engineering have continuously improved the manufacturing process of vaccines， and hepatitis B vaccine has gradually developed from the initial plasma-derived vaccine to the currently used recombinant vaccine. Preventive hepatitis B vaccine has been clinically tested in patients with HBsAg seroclearance to increase the level of anti-HBs， with certain safety and efficacy. As one of the multiple targets for new drugs in the treatment of chronic hepatitis B， a therapeutic hepatitis B vaccine based on HBsAg is already in the stages of research and development and clinical trial.
