Advances in Animal Aging Models
10.12300/j.issn.1674-5817.2022.094
- VernacularTitle:动物衰老模型的研究进展
- Author:
Danyang YIN
1
;
Yi HU
1
;
Rengfei SHI
1
Author Information
1. School of Exercise and Health, Shanghai University of Sport, Shanghai 200438, China
- Publication Type:Journal Article
- Keywords:
Aging;
Animal model;
Evaluation
- From:
Laboratory Animal and Comparative Medicine
2023;43(2):156-162
- CountryChina
- Language:Chinese
-
Abstract:
With the increasing severity of global aging, aging-related issues have become the hotspot in the field of health. In recent years, animal aging models have been widely developed and applied, which is of great significance in the study of aging mechanism. Animals with short life span, such as Caenorhabditis Elegans and Drosophila Melanogaster, have natural advantages in the study of aging. Various rat and mouse aging models have been used in aging studies. In recent years, new animal aging models have been developed, such as the African turquoise killifish. The authors reviewed main animal models used in the study of aging, and analyzed the establishment methods, evaluation indexes, advantages and disadvantages of each model in order to provide reference for related research.
