Mid-to-long term fate of neo-aortic root after arterial switch operation for Taussig-Bing anomaly: A retrospective study in a single center
- VernacularTitle:Taussig-Bing畸形患儿动脉调转术后中远期主动脉根部结局的单中心回顾性研究
- Author:
Mingjun GU
1
,
2
;
Dian CHEN
1
,
2
;
Renjie HU
1
,
2
;
Jie HU
1
,
2
;
Wei DONG
1
,
2
;
Wen ZHANG
1
,
2
;
Qi JIANG
1
,
2
;
Yifan ZHU
1
,
2
;
Haibo ZHANG
1
,
2
Author Information
1. Department of Pediatric Thoracic and Cardiovascular Surgery, Shanghai Children&rsquo
2. s Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, P. R. China
- Publication Type:Journal Article
- Keywords:
Taussig-Bing anomaly;
arterial switch operation;
aortic root dilation;
aortic regurgitation
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2024;31(04):504-509
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore growth pattern of neo-aortic root as well as development of neo-aortic regurgitation after arterial switch operation (ASO) for Taussig-Bing anomaly. Methods From 2002 to 2017, the patients who received ASO, and were discharged alive from Shanghai Children’s Medical Center and followed up for more than 3 years were retrospectively involved in this study. Results A total of 127 patients were enrolled. There were 98 (77.2%) males, the median age at ASO was 73.0 d and the average weight was 4.7 kg. Forty-five (35.4%) children were complicated with mild or mild-to-moderate pulmonary insufficiency (PI) before ASO. The average follow-up time was 7.0 years. During the follow-up, 14 (11.0%) children presented moderate or greater neo-aortic regurgitation (neo-AR). The diameter of neo-aortic annulus and sinus of Valsalva was beyond normal range during the entire follow-up. The average diameter of neo-aortic annulus was 18.0 mm at 5 years and 20.5 mm at 10 years. The average diameter of sinus of Valsalva was 25.9 mm at 5 years and 31.1 mm at 10 years. Neo-AR continued to develop over time. The diameter of children who developed moderate or greater neo-AR was constantly larger than that of children who did not (χ2=18.3, P<0.001). Preoperative mild or mild-to-moderate PI was an independent risk factor for the development of moderate or greater neo-AR during mid-to-long term follow-up (c-HR=3.46, P=0.03). Conclusion The diameters of neo-aortic annulus and sinus of Valsalva of Taussig-Bing children who receive ASO repair continue to expand without normalization. The dilation of annulus correlates with the development of neo-AR. PI before ASO repair increases the risk of neo-AR development.
