Visual Analysis of Research Trends and Hotspots in Animal Models of Chronic Heart Failure
10.19378/j.issn.1003-9783.2024.03.011
- VernacularTitle:慢性心力衰竭动物模型的研究趋势与热点可视化分析
- Author:
Kun LIAN
1
;
Xin LI
;
Siyuan HU
;
Yuehang XU
;
Ji OUYANG
;
Zhixi HU
Author Information
1. 湖南中医药大学,湖南 长沙 410208
- Keywords:
chronic heart failure;
animal model;
research trends;
hotspots;
VOSviewer;
bibliometrics;
visual analysis;
myocardial hypertrophy;
oxidative stress;
myocardial fibrosis
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2024;35(3):394-401
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the research situation of animal model of chronic heart failure(CHF)based on visualization software and bibliometrics methods,and to explore the research hotspots of animal models of CHF and guide the design of animal experiments and scientific research.Methods Literature related to animal model of CHF included in Web of Science core collection from January 1,2001 to October 10,2022 were retrieved.After reading the full text and obtaining the final included literature,VOSviewer and CiteSpace software were used to analyze the contents of institutions,journals and co-cited journals,authors and co-cited authors,keywords.Results A total of 961 papers were included,and the number of published papers increased steadily.The United States and China are the main research countries.Johns Hopkins University and Harvard University are major research institutions.The most frequently published and cited journals are AM J PHYSIOL-HEART C and CIRCULATION,etc..Schultz Harold D and Sabbah Hani N are more influential in author selection."Myocardial infarction","cardiac hypertrophy",and"rat"are the most frequent keywords,10 clusters and 18 emergent words were formed.Conclusion The research in this field is numerous,high quality but scattered.Commonly used animal models are rodents and dogs.The main modeling methods are surgery and drugs.The main pathological mechanisms are mainly myocardial hypertrophy,oxidative stress,and myocardial fibrosis.
