Progress of Paget disease of the vulva
10.3760/cma.j.cn115355-20221004-00618
- VernacularTitle:外阴佩吉特病的研究进展
- Author:
Min WANG
1
;
Jie LI
;
Kexin ZHANG
;
Shuai MA
Author Information
1. 吉林大学第二医院妇产科，长春 130041
- Keywords:
Paget disease, extramammary;
Vulvar neoplasms;
Immunohistochemistry;
Diagnosis;
Prognosis
- From:
Cancer Research and Clinic
2023;35(11):878-880
- CountryChina
- Language:Chinese
-
Abstract:
Paget disease of the vulva is the most common type of extramammary Paget disease and is a rare clinical malignancy occurring in the vulva. At present, the specific pathogenesis is not clear, and the lesions mainly involve areas rich in apocrine sweat glands, such as the external genitalia. The clinical manifestations show no obvious heterogeneity, and may be characterized by erythema, pruritus, scurf and tingling in the lesion area, with erosion and exudation in severe cases. Diagnosis requires histopathological examination and immunohistochemistry. Paget disease of the vulva is often misdiagnosed as eczema or dermatitis due to the lack of knowledge about this disease in clinicians. This article reviews the current research progress of Paget disease of the vulva, in order to deepen clinicians' understanding of this disease and effectively improve clinical diagnosis and treatment abilities.
