Efficacy comparison of remifentanil combined with propofol target-controlled infusion anesthesia and combined intravenous-inhalation anesthesia in patients with ultra-low rectal cancer
10.3760/cma.j.cn115355-20230105-00007
- VernacularTitle:超低位直肠癌患者瑞芬太尼复合丙泊酚靶控输注麻醉与静吸复合麻醉效果比较
- Author:
Hongzhi WANG
1
;
Feng LI
Author Information
1. 山西省肿瘤医院 中国医学科学院肿瘤医院山西医院 山西医科大学附属肿瘤医院麻醉科，太原 030013
- Keywords:
Rectal neoplasms;
Anesthesia;
Remifentanil;
Propofol;
Target-controlled infusion
- From:
Cancer Research and Clinic
2023;35(10):761-764
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the efficacy of combined intravenous-inhalation anesthesia and remifentanil combined with propofol target-controlled infusion anesthesia in ultra-low rectal cancer patients.Methods:The clinical data of 100 patients with ultra-low rectal cancer in Shanxi Province Cancer Hospital from February 2020 to February 2022 were retrospectively analyzed, and the patients were divided into remifentanil combined with propofol target-controlled infusion anesthesia group (target-controlled infusion anesthesia group) and combined intravenous-inhalation anesthesia group according to the anesthesia methods, with 50 patients in each group. The anesthesia effects, respiratory recovery time, eye opening time, anesthesia recovery time, hemodynamics, sedation degrees, mental status and adverse reactions were compared between the two groups.Results:The excellent and good anesthesia rate in the target-controlled infusion anesthesia group was higher than that in the combined intravenous-inhalation anesthesia group [92% (46/50) vs. 76% (38/50)], and the difference between the two groups was statistically significant ( χ2 = 4.76, P < 0.05). The respiratory recovery time, eye opening time and anesthesia recovery time in the target-controlled infusion anesthesia group were shorter than those in the combined intravenous-inhalation anesthesia group (all P < 0.05), and the mean arterial pressure at 30 min of surgery was lower than that in the combined intravenous-inhalation anesthesia group ( P < 0.05). The Ramsay sedation score at 5, 15 and 30 minutes after surgery and the mini-mental state examination score at 1 and 3 days after surgery in the target-controlled infusion anesthesia group were higher than those in the combined intravenous-inhalation anesthesia group (all P < 0.05). The difference in the incidence of adverse reactions between the target-controlled infusion anesthesia group and the combined intravenous-inhalation anesthesia group [6% (3/50) vs. 8% (4/50)] was not statistically significant ( χ2 < 0.01, P > 0.05). Conclusions:The efficacy of remifentanil combined with propofol target-controlled infusion anesthesia is better than that of combined intravenous-inhalation anesthesia for patients with ultra-low rectal cancer.
