Progress of guanylate binding protein 5 in tumors
10.3760/cma.j.cn115355-20230214-00072
- VernacularTitle:鸟苷酸结合蛋白5在肿瘤中的研究进展
- Author:
Mingzhen MA
1
;
Yongbin ZHENG
Author Information
1. 武汉大学人民医院胃肠外Ⅰ科，武汉 430061
- Keywords:
Neoplasms;
Guanylate binding protein 5;
Tumor markers, biological
- From:
Cancer Research and Clinic
2023;35(9):709-712
- CountryChina
- Language:Chinese
-
Abstract:
Malignant tumor ranks as a leading cause of human death. Guanylate binding protein 5 (GBP5) belongs to the family of interferon-γ-inducible large GTPase superfamily and participates in various pathological and physiological processes. A growing number of studies have indicated that GBP5 is involved in the malignant progression of tumors. This article mainly reviews the biological characteristics of GBP5 and its expression, regulation and function in tumors, in the hope of providing a theoretical basis for the diagnosis and treatment of tumors.
