Primary pleural diffuse large B-cell lymphoma:one case report and the review of literatures
10.3781/j.issn.1000-7431.2023.2307-0341
- VernacularTitle:原发胸膜弥漫大B细胞淋巴瘤1例及文献复习
- Author:
Hong ZHENG
1
;
Yudan CHU
;
Xiaojian LIU
Author Information
1. 复旦大学附属肿瘤医院闵行院区肿瘤内科,上海 200240
- Keywords:
Diffuse large B-cell lymphoma;
Pleura;
Case report
- From:
Tumor
2023;43(10):809-812
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To describe the clinical characteristics and diagnosis and treatment process of a patient with primary pleural diffuse large B-cell lymphoma(DLBCL),in order to enhance the understanding of primary pleural DLBCL in clinical practice. Methods:The clinical characteristics and diagnosis and treatment process of a patient with primary pleural DLBCL was reported,and the related literatures were reviewed. Results:The patient complained of chest tightness and shortness of breath for over a year,and chest CT showed left pleural effusion and thickening of the left pleura.Thoracoscopic examination revealed extensive adhesions in the parietal pleura of the chest cavity,diffuse congestion of the parietal pleura,and multiple cauliflower-like new organisms.The pathological biopsy of the pleura diagnosed(left pleural mass)as DLBCL.After diagnosis,R-CHOP combined with Zebutinib treatment was performed for 4 cycles,and mid-term evaluation of chest CT showed significant regression of the tumor. Conclusion:Primary pleural DLBCL is a rare disease.It is easily to be misdiagnosed due to non-specific clinical and imaging manifestations.The final diagnosis depends ultimately on pathological biopsy,and thoracoscopy is the most effective method to confirm DLBCL.
