The application of methylation detection in tumor diagnosis and treatment
10.3760/cma.j.cn114452-20240303-00105
- VernacularTitle:DNA甲基化检测在肿瘤诊疗中的应用
- Author:
Xiaobing XIE
1
;
Yuli LIU
Author Information
1. 湖南中医药大学第一附属医院医学检验与病理中心，长沙410007
- Keywords:
DNA methylation;
RNA methylation;
Malignant tumor
- From:
Chinese Journal of Laboratory Medicine
2024;47(4):349-352
- CountryChina
- Language:Chinese
-
Abstract:
Cancer-specific target gene methylation detection technology has shown good application prospects and development in early cancer screening, selection of therapeutic drugs, efficacy monitoring, and prediction of prognosis. Taking the diagnosis and treatment of cancer including lung cancer, liver cancer and ovarian cancer, etc. as the entry point of cancer-specific target gene methylation clinical research, highlighting the clinical significance of methylation biomarkers in early screening, differential diagnosis, and prediction of recurrence of tumors.Research on the biological significance and clinical approaches of cancer-specific targeted gene methylation in tumors, as well as conducting prospective large-scale clinical studies, holds great promise to transform it into important biomarkers for clinical diagnosis and treatment in the future.
