Research and application of Surface-enhanced Raman scattering technique in biomedical detection
10.3760/cma.j.cn114452-20230927-00177
- VernacularTitle:表面增强拉曼散射技术在生物医学检测中的研究及应用
- Author:
Xiaojing YIN
1
;
Chuanli REN
;
Chongxu HAN
;
Pan YANG
;
Lin ZHOU
;
Weiling FU
;
Yang ZHANG
Author Information
1. 扬州大学临床医学院/江苏省苏北人民医院医学检验科，扬州225000
- Keywords:
Spectrum analysis, Raman;
Tumor diagnosis;
Pathogen detection;
Biomolecular detection
- From:
Chinese Journal of Laboratory Medicine
2024;47(3):314-322
- CountryChina
- Language:Chinese
-
Abstract:
The application of Raman spectroscopy in the field of laboratory medicine is making continuous progress and development. The biosensor platform based on Raman spectroscopy provides a new means for accurate molecular diagnosis of diseases. In particular, as a fast and non-destructive detection method, surface-enhanced Raman scattering has the advantages of simple sample preparation, little interference from water and real-time detection, and shows great application potential in the field of medical examination. At the same time, with the integration of SERS and other technologies, including electrochemistry, new nano-materials, microfluidic, biochip, DNA nano-machine, artificial intelligence and machine learning, it will play a more and more important role in the field of medical laboratory. With the deepening of SERS research and the cross-integration between multiple disciplines, it will be widely used in biomedical detection and is expected to become an important technology platform for the next generation of precision diagnosis.
