Laboratory diagnosis and clinical applications of hepatitis E
10.3760/cma.j.cn114452-20231130-00316
- VernacularTitle:戊型肝炎的实验室诊断指标与临床应用
- Author:
Dong YING
1
;
Ningshao XIA
;
Zizheng ZHENG
Author Information
1. 厦门大学公共卫生学院/生命科学学院,国家传染病诊断试剂与疫苗工程技术研究中心,国家药监局传染性疾病检测技术研究与评价重点实验室,厦门361104
- Keywords:
Hepatitis E virus;
Hepatitis E antibody;
Hepatitis E antigen;
Etiological diagnosis
- From:
Chinese Journal of Laboratory Medicine
2024;47(3):210-215
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis E virus (HEV) is the major pathogen responsible for acute viral hepatitis in China. Recently, there have been new advances in the methodologies and novel discoveries in the laboratory diagnosis of HEV, including various diagnostic markers such as HEV RNA, HEV antigen, anti-HEV IgM, and anti-HEV IgG. A multi-indicator diagnostic approach should be applied across different populations, including patients with acute or chronic hepatitis E, individuals with extra-hepatic clinical symptoms, asymptomatic carriers, and specific occupational groups undergoing health assessments. The clinical significance of test results for each marker varies among these different groups.