A case of neonatal bloodstream infection caused by Salmonella enterica subsp .enterica Serovar Worthington Strain

VernacularTitle:新生儿肠沙门菌肠道亚种沃兴顿株引起血流感染1例
Author: Longfeng QU ¹ ; Yayun ZHANG
Author Information

1. 重庆大学附属江津医院检验科，重庆　402260
Keywords: Salmonella; Serotyping; Blood stream infection
From: Chinese Journal of Laboratory Medicine 2024;47(2):184-186
CountryChina
Language:Chinese
Abstract: The patient was a 6-day-and-19-hours-old girl. On March 31, 2023, she was admitted to Chongqing University JiangJin Hospital with symptoms of yellow skin staining for 3 days and fever for 6 hours. On April 1st, the Medicine Laboratory reported a critical value in blood cultures: Gram-negative bacilli, which were identified as Salmonella through mass spectrometry and biochemical tests. It was classified as non A-F group Salmonella due to negative AF and Vi serotyping results. Subsequent serum agglutination test after subculture showed O13, 23 Hz, l, w, and further results by analysis using the sequences of the 16S rRNA and gyrB genes confirmed it as Salmonellaenterica subsp. enterica Serovar Worthington Strain, consistent with the serum agglutination test result. After receiving a 14-day course of Ampicillin/Sulbact treatment for infection control, the patient′s health condition improved she was discharged from the hospital. The identification of Salmonella requires simultaneous bacterial biochemical identification and serological tests ser to ensure accurate results and provide reliable basis for etiological diagnosis.