Mycobacterium tuberculosis extracellular vesicles: diagnostic, preventive and therapeutic potential
10.3760/cma.j.cn114452-20231106-00260
- VernacularTitle:结核分枝杆菌胞外囊泡：诊断、预防和治疗潜力
- Author:
Fengjuan WANG
1
;
Lei ZHOU
;
Jiayun LIU
Author Information
1. 空军军医大学第一附属医院检验科，西安 710032
- Keywords:
Mycobacterium tuberculosis;
Vesicles;
Biomarkers;
Diagnosis;
Therapeutic
- From:
Chinese Journal of Laboratory Medicine
2024;47(1):98-104
- CountryChina
- Language:Chinese
-
Abstract:
By summarizing the biological formation and component function of Mycobacterium tuberculosis extracellular vesicles, this manuscript discusses the potential usage of Mycobacterium tuberculosis extracellular vesicles in diagnosis, prevention, and treatment of tuberculosis. It is concluded that both Mycobacterium tuberculosis membrane vesicles and exosomes secreted by the host contain the components of Mycobacterium tuberculosis to participate in immune regulation, and play different roles in the diagnosis, prevention, and treatment of tuberculosis. Mycobacterium tuberculosis extracellular vesicles contain abundant biomarkers and have natural immunogenicity, which are expected to become new targets for diagnosis, prevention, and treatment of tuberculosis.
