Production mechanism,clinical research and application of tumor related autoantibodies
10.3760/cma.j.cn114452-20230923-00160
- VernacularTitle:肿瘤相关自身抗体的产生机制及临床研究与应用
- Author:
Haizhou ZHOU
1
;
Xiuru GUAN
Author Information
1. 哈尔滨医科大学附属第一医院检验科,哈尔滨 150001
- Keywords:
Tumor-associated;
Autoantibodies;
Antigen;
Biomarkers
- From:
Chinese Journal of Laboratory Medicine
2023;46(11):1123-1127
- CountryChina
- Language:Chinese
-
Abstract:
Tumor-associated autoantibodies (TAAS), as cancer biomarkers, have attracted special attention. In recent years, increasing evidence has indicated that TAAS shows an elevated level in the early stage of human malignancies, and examination of TAAS in patients′ clinical specimens has a good predictive value for a variety of cancers′ early diagnosis. The mechanism of TAAS and its clinical application will be introduced, and the advantages and problems of tumor autoantibodies as markers will be expounded in this article.