Research progress on the safety of scleral collagen cross-linking in the prevention and control of pathological myopia
10.3760/cma.j.cn511434-20230504-00199
- VernacularTitle:巩膜胶原交联技术在防控病理性近视安全性方面的研究进展
- Author:
Qingqiang WANG
1
;
Xiaojun DU
;
Xinguo JIA
;
Guoying MU
;
Ruolan LIU
;
Chunli CHEN
Author Information
1. 山东省东营市胜利油田中心医院眼科，东营 257000
- Keywords:
Scleral collagen crosslinking;
Pathological myopia;
Safety;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2024;40(1):76-80
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of myopia is increasing year by year and the trend of younger age is obvious. The situation of myopia prevention and control is very serious. The sclera is the target organ for the development of myopia. When myopia occurs and develops, the ultrastructure of the sclera tissue will undergo pathological changes, resulting in a decrease in its tensile strength, then progressive axial growth and posterior sclera expansion. Scleral collagen cross-linking can effectively increase the hardness and tensile strength of scleral tissue, which may have great potential in the prevention and control of myopia, especially pathological myopia. At present, the effectiveness of scleral collagen cross-linking technology in the prevention and treatment of pathological myopia researches are still in the stage of animal experiments, and there are a lot of controversies on the safety. The development of any new technology to ensure safety is the primary condition. A comprehensive understanding of the safety of scleral collagen crosslinking in the prevention and control of myopia can provide more basis and guidance for the further study of scleral collagen crosslinking.
