Research progress on the ocular adverse effects associated with immune checkpoint inhibitor therapy
10.3760/cma.j.cn511434-20230313-00120
- VernacularTitle:免疫检查点抑制剂治疗相关眼部不良反应的研究进展
- Author:
Weiyan GUO
1
;
Xuemei LIN
;
Songdi WU
Author Information
1. 西北大学附属第一医院（西安市第一医院）神经眼科, 西安 710002
- Keywords:
Immune checkpoint inhibitors;
Ocular adverse effect;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2023;39(12):1033-1038
- CountryChina
- Language:Chinese
-
Abstract:
Immune checkpoint inhibitors (ICI) have revolutionized the field of oncology by regulating the interaction between immune cells and cancer cells and promoting the disinhibition of the immune system, thus targeting various types of malignant tumors. However, the regulation of the immune system can also trigger related adverse reactions. Currently, there are no specific clinical guidelines for the treatment of these adverse reactions. Treatment decisions largely depend on clinical judgment and experience.The pathogenesis of ICI-related ocular adverse events is not fully understood at present. Further research on the specific mechanisms of action can provide new insights into the early diagnosis and treatment of ICI-related ocular adverse events.
