A Case of Graves' Disease Occurring after Subacute Thyroiditis.
10.3904/kjm.2015.89.2.225
- Author:
Hye Mi SEO
1
;
Jong Wook BEOM
;
Su Hee KIM
;
So Yeon YOU
;
Ji Young KIM
;
Gwan Pyo KOH
;
Sang Ah LEE
Author Information
1. Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea. salee@jejunu.ac.kr
- Publication Type:Case Report
- Keywords:
Thyroiditis, Subacute;
Graves disease;
Immunoglobulins, Thyroid-stimulating
- MeSH:
Adult;
Antibodies;
Deglutition;
Female;
Graves Disease*;
Humans;
Hyperthyroidism;
Immunoglobulins, Thyroid-Stimulating;
Methimazole;
Neck Pain;
Receptors, Thyrotropin;
Steroids;
Thyroid Function Tests;
Thyroid Gland;
Thyroiditis, Subacute*;
Thyrotropin;
Thyroxine
- From:Korean Journal of Medicine
2015;89(2):225-228
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Graves' disease following subacute thyroiditis is uncommon. Some patients in these cases showed positive for thyroid antibody only transiently in the resolving phase. However, Graves' disease can rarely be caused by the presence of antibodies after subacute thyroiditis, although the pathophysiology of this is unclear. A 40-year-old woman presented with anterior neck pain and swallowing difficulty. Thyroid function testing showed reduced thyroid-stimulating hormone (TSH) and elevated free thyroxine levels. A thyroid scan revealed decreased uptake in the bilateral thyroid gland. The patient was initially diagnosed with subacute thyroiditis and treated with steroids. Five months later, thyroid function testing showed recurrent hyperthyroidism with positive conversion of TSH receptor antibody, indicating Graves' disease. Since then, she needed the long-term methimazole treatment. In summary, we herein report a case of Graves' disease occurring after subacute thyroiditis.
