Exploration of surgical treatment indications for invasive pulmonary aspergillosis and mucormycosis in children
10.3760/cma.j.cn112434-20230606-00119
- VernacularTitle:儿童侵袭性肺部曲霉菌及毛霉菌病外科治疗指征的探讨
- Author:
Dingyi LIU
1
;
Qi ZENG
;
Chenghao CHEN
;
Na ZHANG
;
Jie YU
;
Dong YAN
;
Changqi XU
;
Qian ZHANG
;
Xu ZHANG
Author Information
1. 国家呼吸系统疾病临床医学研究中心 儿科重大疾病研究教育部重点实验室 国家儿童医学中心 首都医科大学附属北京儿童医院胸外科，北京 100045
- Keywords:
Invasive pulmonary aspergillosis;
Invasive pulmonary mucormycosis;
Operation indication
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2024;40(2):85-88
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To review and analyze clinical data of patients with invasive pulmonary aspergillosis and mucormycosis, and to explore the surgical indication.Methods:Clinical data of 10 patients with invasive pulmonary aspergillosis and mucormycosis were analyzed retrospectively from March 2018 to November 2022 in our hospital, Department of Thoracic Surgery.Results:The age of children varied from 2.58 years old to 16.00 years old and 6 children were males while 4 females. Five patients suffer from invasive pulmonary aspergillosis. Five patients suffer from invasive pulmonary mucormycosis. The operative indication of 7 patients was the risk of massive bleeding in the airway. The surgical indication for two patients is to control infection and continue treating malignant tumors. One patient chose surgical treatment because the infection could not be cured after long-term antifungal treatment but the focus was limited. Two patients died of sudden acute hemoptysis before operation, the prognosis of 8 patients undergoing surgical treatment was good.Conclusion:The lethal rate of invasive pulmonary aspergillosis and mucormycosis is very high. Antifungal drug treatment combined with timely surgical treatment can save patients lives.
