Analysis of risk factors for poor prognosis of congenital heart disease in neonates
10.3760/cma.j.cn112434-20230627-00130
- VernacularTitle:新生儿先天性心脏病术后不良预后危险因素分析
- Author:
Han ZHANG
1
;
Gang LI
;
Jiachen LI
;
Yansong ZUO
;
Qiang WANG
Author Information
1. 首都医科大学附属北京安贞医院小儿心脏中心，北京 100029
- Keywords:
Neonate;
Congenital heart disease;
Lactate;
Vasocative-ventilation-renal score;
Prognosis
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2024;40(1):34-41
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effective indicators that can predict the poor prognosis of neonates with congenital heart disease after surgery.Methods:178 cases of neonatal congenital heart disease were retrospectively analyzed. According to the outcome, they were divided into normal prognosis group (132 cases) and poor prognosis group (46 cases).Results:15 (8.4%) patients died in hospital. There were statistical differences between the two groups in terms of whether PGE and vasoactive drugs were needed before surgery, preoperative respiratory support mode, blood lactate level from anesthesia induction to 24 h after surgery, VIS and VVR scores, whether delayed sternal closure or peritoneal dialysis were needed ( P<0.05). Logistic regression analysis showed that elevated lactate levels and VVR scores on 24 h after surgery were independent risk factors for death or other poor postoperative prognosis in neonates ( P<0.05). Conclusion:The levels of lactate and VVR scores in 24 h after operation are sensitive indicators for monitoring the severity of the condition, guiding treatment and judging prognosis of neonatal congenital heart disease surgery.
