Effects of a botulinum toxin type A injection on the masseter muscle: An animal model study.
10.1186/s40902-015-0010-8
- Author:
Si Yeok PARK
1
;
Young Wook PARK
;
Young Jun JI
;
Sung Wook PARK
;
Seong Gon KIM
Author Information
1. Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University, Gangneung, Republic of Korea.
- Publication Type:Original Article
- Keywords:
Botulinum toxin type A;
Electromyography;
Masseter muscle;
Peak voltage
- MeSH:
Adult;
Botulinum Toxins, Type A*;
Electromyography;
Humans;
Male;
Masseter Muscle*;
Models, Animal*;
Rabbits
- From:Maxillofacial Plastic and Reconstructive Surgery
2015;37(3):10-
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The aim of this study was to investigate the effect of a botulinum toxin type A (BTX-A) injection in the masseter muscle using electromyography (EMG) in an animal model. METHODS: Ten male adult (>3 months of age) New Zealand white rabbits were used. Muscle activity was continuously recorded from 8 hours before to 8 hours after BTX-A injection. The rabbits received unilateral BTX-A injections of either 5 units (group 1, n = 5) or 20 units (group 2, n = 5). RESULTS: The masseter muscle activity of the rabbits was significantly reduced immediately after BTX-A injection (P < 0.05 for both groups). When the results from group 1 were compared with those from group 2, only the peak voltage was significantly decreased in group 2 (P = 0.013). CONCLUSION: Masseter muscle activity measured by EMG was immediately decreased after a BTX-A injection.
