Systematic analysis of epidemiological features of norovirus causing sporadic acute gastroenteritis in China
10.3760/cma.j.cn112309-20231027-00110
- VernacularTitle:我国诺如病毒急性胃肠炎散发病例流行病学系统性分析
- Author:
Zehua LEI
1
;
Xuefeng ZHANG
;
Junwei HOU
;
Yanan HOU
;
Sensen YANG
;
Zhijing MA
;
Yu LIANG
;
Jing ZHANG
;
Qiming LI
Author Information
1. 国药中生生物技术研究院（新型疫苗国家工程研究中心）第六研究室，北京 101111
- Keywords:
Norovirus;
Sporadic;
Acute gastroenteritis;
Literature review
- From:
Chinese Journal of Microbiology and Immunology
2023;43(12):961-968
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate the prevalence of norovirus causing sporadic acute gastroenteritis in China.Methods:Relevant articles on acute gastroenteritis caused by norovirus in China published between January 2010 and October 2023 were retrieved from Wanfang, CNKI and PubMed database. The articles met inclusion and exclusion criteria were enrolled in this study. Excel software and SPSS20.0 software were used for statistical analysis. The epidemiological features of sporadic cases of acute gastroenteritis caused by norovirus in China were summarized using descriptive statistical analysis.Results:A total of 500 articles were included in this study, involving 784 486 cases of acute gastroenteritis and 670 292 samples in 32 provinces and regions. Norovirus GⅡ was the predominant genogroup causing acute gastroenteritis in China in recent years, but there were significant differences in the distribution of genotypes and epidemic strains at different times. GⅡ.4 was the predominant genotype in each year, and GⅡ.4/2006b and GⅡ.4 /Sydney_2012 were the main epidemic strains. Norovirus-related diarrhea occurred throughout the year, especially between the months of October and December. The incidence of norovirus infection was high in children under five years old and varied in different regions.Conclusions:Norovirus GⅡ was the predominant genogroup causing norovirus-related sporadic acute gastroenteritis in China, but there was an obvious genetic evolutionary trend in the epidemic strains. Factors such as epidemic strains, season and geographical region should be considered when making strategies for the prevention and control of norovirus-related diarrhea and developing vaccines.
