The effects of theta burst transcranial magnetic stimulation and rehabilitation training in different sequences on the upper limb functioning of stroke survivors
10.3760/cma.j.issn.0254-1424.2024.03.006
- VernacularTitle:不同介入顺序的间歇性Theta爆发式经颅磁刺激与康复训练对脑卒中患者上肢功能的影响
- Author:
Jiaojiao WU
1
;
Ying HAN
;
Linhong MO
;
Yiqiu NIE
;
Aixian LIU
Author Information
1. 首都医科大学附属北京康复医院神经康复中心，北京 100144
- Keywords:
Theta burst magnetic stimulation;
Transcranial magnetic stimulation;
Stroke;
Upper limb motor function;
Rehabilitation training
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2024;46(3):221-225
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore any effect of intermittent theta burst stimulation (iTBS) and of different sequencing of rehabilitation training on upper limb dysfunction after a stroke.Methods:Thirty-six patients with upper limb motor dysfunction after subacute subcortical cerebral infarction were divided at random into a control group, an experimental group 1, and an experimental group 2, each of 12. The control group was given prosthetic stimulation and upper limb function rehabilitation training. Experimental group l received focal iTBS stimulation on M1 immediately followed by upper limb rehabilitation training. Experimental group 2 received the same treatment but in reverse order. The experiment lasted four weeks. Upper limb functioning and ability in the activities of daily living (ADL) were quantified before and after the interventions using the Fugl-Meyer upper extremity assessment (FMA-UE) and the modified Barthel index (MBI). Cortical latency (CL) was also recorded.Results:Before the treatment there were no significant differences among the three groups, but afterward a significant increase was observed in the average FMA-UE and MBI scores of both experimental groups accompanied by a significant decrease in CL. There was no significant difference between the two experimental groups′ results, on average.Conclusion:Supplementing upper limb rehabilitation training with iTBS can significantly improve the upper limb functioning of ischemic stroke survivors, and the sequencing of the training has no effect on the therapeutic results.
